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Image Search Results
Journal: mAbs
Article Title: Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors
doi: 10.1080/19420862.2024.2402701
Figure Lengend Snippet: Comparison of two sets of CD20 antibodies binding to FcγRI from different species. (a) human, (b) cynomolgus monkey, (c) mouse. Binding was measured by surface plasmon resonance and expressed as a percentage of the binding of wild-type IgG1. Sample set 1 was prepared in HEK cells and sample set 2 in CHO cells.
Article Snippet:
Techniques: Comparison, Binding Assay, SPR Assay
Journal: mAbs
Article Title: Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors
doi: 10.1080/19420862.2024.2402701
Figure Lengend Snippet: Comparison of the binding of CD20 antibodies to human fc receptors and their activity in a cell-based luminescence assay. (a) FcγRI, (b) FcγRIIa (131 H), (c) FcγRIIa (131 R), (d) FcγRIIb, (e) FcγRIIIa (158F), (f) FcγRIIIa (158 V). Binding and activity are expressed as a percentage of wild-type IgG1. Wild-type IgG3 is indicated with an open square □, other samples with a closed circle ●.
Article Snippet:
Techniques: Comparison, Binding Assay, Activity Assay, Luminescence Assay
Journal: mAbs
Article Title: Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors
doi: 10.1080/19420862.2024.2402701
Figure Lengend Snippet:
Article Snippet:
Techniques:
Journal: mAbs
Article Title: Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors
doi: 10.1080/19420862.2024.2402701
Figure Lengend Snippet:
Article Snippet:
Techniques: