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Comparison of two sets of CD20 antibodies binding to <t>FcγRI</t> from different species. (a) human, (b) cynomolgus monkey, (c) mouse. Binding was measured by surface plasmon resonance and expressed as a percentage of the binding of wild-type IgG1. Sample set 1 was prepared in HEK cells and sample set 2 in CHO cells.
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Comparison of two sets of CD20 antibodies binding to <t>FcγRI</t> from different species. (a) human, (b) cynomolgus monkey, (c) mouse. Binding was measured by surface plasmon resonance and expressed as a percentage of the binding of wild-type IgG1. Sample set 1 was prepared in HEK cells and sample set 2 in CHO cells.
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Promega mouse fcγriv and nfat luciferase reporter
Comparison of two sets of CD20 antibodies binding to <t>FcγRI</t> from different species. (a) human, (b) cynomolgus monkey, (c) mouse. Binding was measured by surface plasmon resonance and expressed as a percentage of the binding of wild-type IgG1. Sample set 1 was prepared in HEK cells and sample set 2 in CHO cells.
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Promega fcγriv cell–based adcc reporter assay
Comparison of two sets of CD20 antibodies binding to <t>FcγRI</t> from different species. (a) human, (b) cynomolgus monkey, (c) mouse. Binding was measured by surface plasmon resonance and expressed as a percentage of the binding of wild-type IgG1. Sample set 1 was prepared in HEK cells and sample set 2 in CHO cells.
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Image Search Results


Comparison of two sets of CD20 antibodies binding to FcγRI from different species. (a) human, (b) cynomolgus monkey, (c) mouse. Binding was measured by surface plasmon resonance and expressed as a percentage of the binding of wild-type IgG1. Sample set 1 was prepared in HEK cells and sample set 2 in CHO cells.

Journal: mAbs

Article Title: Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors

doi: 10.1080/19420862.2024.2402701

Figure Lengend Snippet: Comparison of two sets of CD20 antibodies binding to FcγRI from different species. (a) human, (b) cynomolgus monkey, (c) mouse. Binding was measured by surface plasmon resonance and expressed as a percentage of the binding of wild-type IgG1. Sample set 1 was prepared in HEK cells and sample set 2 in CHO cells.

Article Snippet: FcγRI (CD64) , human , Promega , GA133A.

Techniques: Comparison, Binding Assay, SPR Assay

Comparison of the binding of CD20 antibodies to human fc receptors and their activity in a cell-based luminescence assay. (a) FcγRI, (b) FcγRIIa (131 H), (c) FcγRIIa (131 R), (d) FcγRIIb, (e) FcγRIIIa (158F), (f) FcγRIIIa (158 V). Binding and activity are expressed as a percentage of wild-type IgG1. Wild-type IgG3 is indicated with an open square □, other samples with a closed circle ●.

Journal: mAbs

Article Title: Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors

doi: 10.1080/19420862.2024.2402701

Figure Lengend Snippet: Comparison of the binding of CD20 antibodies to human fc receptors and their activity in a cell-based luminescence assay. (a) FcγRI, (b) FcγRIIa (131 H), (c) FcγRIIa (131 R), (d) FcγRIIb, (e) FcγRIIIa (158F), (f) FcγRIIIa (158 V). Binding and activity are expressed as a percentage of wild-type IgG1. Wild-type IgG3 is indicated with an open square □, other samples with a closed circle ●.

Article Snippet: FcγRI (CD64) , human , Promega , GA133A.

Techniques: Comparison, Binding Assay, Activity Assay, Luminescence Assay

Journal: mAbs

Article Title: Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors

doi: 10.1080/19420862.2024.2402701

Figure Lengend Snippet:

Article Snippet: FcγRI (CD64) , human , Promega , GA133A.

Techniques:

Journal: mAbs

Article Title: Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors

doi: 10.1080/19420862.2024.2402701

Figure Lengend Snippet:

Article Snippet: FcγRI (CD64) , human , Promega , GA133A.

Techniques: